Hospitalized patients accepting All Out Parenteral Sustenance (TPN) are in danger of building up a few nosocomial contaminations, and to be specific candidemia. This investigation meant to evaluate this rate in a solitary focus in Saudi Arabia and to investigate potential hazard factors. A review survey including all patients confessed to Ruler Abdulaziz College Medical clinic in Jeddah, Saudi Arabia, somewhere in the range of 2014 and 2015, and who was on TPN. One hundred and sixteen patients were incorporated into this examination. Male patients comprised (62.1%), and with a mean period of (55.6 ± 18.4) years. The occurrence of candidemia was (11.2%). TPN length was essentially longer in patients who tried positive for candidemia (26.1±21.2 days) when contrasted with the individuals who tried negative (14.2±11.7 days; P = 0.002). As to factors; a past filled with strong organ danger, or being on corticosteroids before TPN were both fundamentally connected with being sure for candidemia (P=0.004 and P=0.019, separately). Hospitalized patients accepting TPN are in danger of candidemia, particularly those on delayed TPN or those on corticosteroids. Patients on TPN ought to be overseen by a specific and devoted healthful help group.